Dear Rakha,
No, the CR120 cannot operate horizontally with the pump facing upward.
In this position, water cannot fully enter the pump, which may cause the pump to fail.
However, the CR120 can operate horizontally with the pump facing down.
You can use the brackets that come with the reservoir.
Please download and refer to the installation guide.
If you have any questions, feel free to contact us.
https://shop.bitspower.com/index.php?route=product/product&product_id=8729&search=CR120